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rotem delta® instrument  (Tem Innovations GmbH)

 
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    Tem Innovations GmbH rotem delta® instrument
    Rotem Delta® Instrument, supplied by Tem Innovations GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rotem+delta%C2%AE+instrument/rotem/pmc09677286-87-10-12
    Average 90 stars, based on 1 article reviews
    rotem delta® instrument - by Bioz Stars, 2026-10
    90/100 stars

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    other:

    Article Title: Endothelial Cell Activation and Thrombin Generation Assessment for the Risk of Severe Early Onset Preeclampsia. the ROADMAP-EOP Study
    Article Snippet: Thromboelastometry was performed on fresh citrated whole blood on ROTEM delta® instrument (Tem Innovations GmbH, Werfen, Munich, Germany).



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    Platelet responses to collagen and CRP-XL in patients stratified by clinical outcome and presence of coagulopathy. (A) Area coverage after adhesion to type 1 collagen under flow conditions in survivors (n = 10) and nonsurvivors (n = 4). (B-C) Aggregation in response to type 1 (Horm) collagen (B) and CRP-XL (C) in survivors (n = 13) and nonsurvivors (n = 7). (D-E) Correlation between adhesion to collagen under flow and CA5 on ROTEM in the presence of tissue factor (EXTEM; D) and after subtraction of cytochalasin D assay to isolate platelet contribution to CA5 (EXTEM-FIBTEM; E). (F-G) Aggregation in response to collagen (F) and CRP-XL (G) in patients with (n = 13) and without (n = 7) TIC. Student t test (A) or 2-way ANOVA with Šidák’s multiple-comparisons test (B-C,F-G). *P < .05; **P < .01; ***P < .001.

    Journal: Blood Advances

    Article Title: Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients

    doi: 10.1182/bloodadvances.2020001776

    Figure Lengend Snippet: Platelet responses to collagen and CRP-XL in patients stratified by clinical outcome and presence of coagulopathy. (A) Area coverage after adhesion to type 1 collagen under flow conditions in survivors (n = 10) and nonsurvivors (n = 4). (B-C) Aggregation in response to type 1 (Horm) collagen (B) and CRP-XL (C) in survivors (n = 13) and nonsurvivors (n = 7). (D-E) Correlation between adhesion to collagen under flow and CA5 on ROTEM in the presence of tissue factor (EXTEM; D) and after subtraction of cytochalasin D assay to isolate platelet contribution to CA5 (EXTEM-FIBTEM; E). (F-G) Aggregation in response to collagen (F) and CRP-XL (G) in patients with (n = 13) and without (n = 7) TIC. Student t test (A) or 2-way ANOVA with Šidák’s multiple-comparisons test (B-C,F-G). *P < .05; **P < .01; ***P < .001.

    Article Snippet: Thromboelastometry Rotational thromboelastometry (ROTEM delta instrument; Rotem, Leipzig, Germany) was performed with citrated whole blood after addition of tissue factor in the presence (FIBTEM) and absence (EXTEM) of the actin polymerization inhibitor cytochalasin D. The platelet contribution to each parameter was calculated by subtracting the FIBTEM value from the EXTEM value, as previously described.

    Techniques: FIBTEM Assay

    sGPVI levels in trauma patients stratified by injury severity and coagulopathy. (A) sGPVI levels in patients with moderate (ISS ≤25; n = 13) and critical (ISS >25; n = 17) injuries. (B) sGPVI levels in patients with (n = 19) and without (n = 11) TIC. (C-D) Correlation between sGPVI levels and CA5 on ROTEM EXTEM (C) and plasma fibrinogen level (D). Bars indicate the mean with 95% CI. Student t test. *P < .05.

    Journal: Blood Advances

    Article Title: Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients

    doi: 10.1182/bloodadvances.2020001776

    Figure Lengend Snippet: sGPVI levels in trauma patients stratified by injury severity and coagulopathy. (A) sGPVI levels in patients with moderate (ISS ≤25; n = 13) and critical (ISS >25; n = 17) injuries. (B) sGPVI levels in patients with (n = 19) and without (n = 11) TIC. (C-D) Correlation between sGPVI levels and CA5 on ROTEM EXTEM (C) and plasma fibrinogen level (D). Bars indicate the mean with 95% CI. Student t test. *P < .05.

    Article Snippet: Thromboelastometry Rotational thromboelastometry (ROTEM delta instrument; Rotem, Leipzig, Germany) was performed with citrated whole blood after addition of tissue factor in the presence (FIBTEM) and absence (EXTEM) of the actin polymerization inhibitor cytochalasin D. The platelet contribution to each parameter was calculated by subtracting the FIBTEM value from the EXTEM value, as previously described.

    Techniques: Clinical Proteomics